External validation for the prediction of incident symptomatic knee Osteoarthritis (OA) in Rotterdam Study-III-1
| Selected Predictors | Study Population (n = 264) | |
|---|---|---|
| OR (95% CI) | P Value | |
| Age (years) | 1.13 (0.93–1.37) | .22 |
| BMI (kg/m2) | 1.09 (0.97–1.22) | .15 |
| Mild knee symptoms* | 1.53 (0.49–5.08) | .44 |
| Knee problems while climbing stairs† | 4.47 (1.31–15.23) | .02 |
| Morning stiffness‡ | 2.14 (0.68–6.73) | .19 |
| Postmenopausal status | 1.33 (0.22–7.98) | .76 |
| Physically demanding work§ | 1.50 (0.50–4.53) | .48 |
| AUC of the model | 0.81 (0.71–0.90) | |
| Calibration: Hosmer-Lemeshow P value | .17 | |
| Variance explained (Nagelkerke), % | 21.9 | |
AUC, area under the curve of the receiver operating characteristic; BMI, body mass index; CI, confidential interval; OR, odds ratio.
Bold indicates P < .05.
↵* Pain in or around the knee within the last 12 months.
↵† Defined with the Knee Injury and Osteoarthritis Outcome Score (KOOS) on physical functioning.
↵‡ Defined with the KOOS on stiffness.
↵§ Defined as doing intense work (regularly lifting heavy objects at work).